Development of High Sensitivity Fluorescent Detection System


We are going to develop a novel flourescence detection system based on con-focal scanning device with high sensitivity to microarray readout. The probe molecules are placed with special pattern, so that the flourescence emission image pattern has this specific geometry. The Image processing method such as matched filtering will be applied to aprove the SNR of flourescence signal. Numerical analysis of optical flied is also performed to optimize the optical design of the system.